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. 2015 Aug 14;10(8):e0136061. doi: 10.1371/journal.pone.0136061

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© 2015 Nadrah et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 1 — A, Developing B cell subsets in BM examined by IgM and IgD cell surface expression by flow cytometry. Cells were previously gated as live (DAPI^-) CD19⁺ cells. B, Enumeration of developing B cell subsets in BM (left), blood (center) and spleen (right) of Socs3 ^+/+ (white) or Socs3 ^fl/fl (red) Mb1 ^Cre/+ mice at 8–10 weeks of age. Bars indicate average, circles depict individual mice. Data were pooled from 4 independent experiments. C, Socs3 expression in proB cells from Socs3 ^+/+ (white) or Socs3 ^fl/fl (red) Mb1 ^Cre/+ mice. Expression is relative to Hprt. Bars indicate average, circles depict individual mice. ns (not significant; unpaired two-tailed student’s t test).