Table 4. IC50 and KD values of IgGs.
| IgG | 10B12 1 | 10F9 1 | 11D8 1 | 7C8 2 | ING2 2 |
|---|---|---|---|---|---|
| IC50 (× 10−9 M) 3 (95% CI) | 73.8 (11.86–41.34) | 8.3 (7.55–91.12) | 20.2 (6.08–73.07) | 1.05 (0.08–0.87) | 2.05 (0.47–5.71) |
| KD. (× 10−9 M) 4 (95% CI) | 44.59 (<87.71) | 9.81 (<24.92) | 20.85 (13.99–30.11) | 1.39 (1.18–1.62) | 115.43 (93.62–134.99) |
1 Measurements were performed in the FRET buffer.
2 Measurements were performed in the KGlu buffer.
3 Determined using FRET and YsCsY, performed in triplicate
4 Results of binding to BoNT/A LC from a single measurement using KinExA.