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. 2015 Aug 14;10(8):e0134672. doi: 10.1371/journal.pone.0134672

Fig 4. Rb1 expression is repressed in cis in Rb1_PPP1R26P1 heterozygous mice.

Fig 4

A) Hybrid control breeding of C57BL/6J and 129 animals in both directions. The maternal genotype is always written on the left side. Expression was analyzed in brain, kidney and liver. Results of all tissues are pooled in one boxplot. B) Comparison of allelic Rb1 expression in hybrid control breeding (pooled results from A) with Rb1_PPP1R26P1 mice. Analysis was performed after maternal or paternal transmission of PPP1R26P1 in brain, kidney and liver; all measurements are depicted in one boxplot. Rb1_PPP1R26P1 mice show significant skewing in favor of the wildtype C57BL/6J (T) allele. Grey dots: female animlas, black dots: male animals. Bee swarm boxplots show the median (given in numbers below the diagram), the quartiles and p-values were calculated using Welch’s t-test.