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. 2015 Aug 14;11(8):e1005466. doi: 10.1371/journal.pgen.1005466

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© 2015 Feliciello et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 5 — Transcripts of TCAST1 satellite DNA, specifically induced after heat stress, are processed into siRNA which target via sequence identity dispersed TCAST1 elements associated with genes. By guiding chromatin modifiers TCAST1 siRNAs increase the level of silent heterochromatin marks at dispersed TCAST1 elements and proximal regions. Temporary assembly and spreading of heterochromatin suppresses activity of nearby genes. Genes associated with elements 2 and 21 are schematically shown: exons are represented by rectangles, elements TCAST1 by arrows and complex containing TCAST1 siRNAs by a circle.