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. 2015 Aug 14;10(8):e0135042. doi: 10.1371/journal.pone.0135042

Table 2. Patient characteristics categorized by age.

Age groups a Total p
<65 65≦<75 75≦
(N = 1472) (N = 1279) (N = 961) (N = 3712)
Gender
    Male (%) 762(51.8) 709(55.4) 491(51.1) 1962(52.9) 0.07
    Female (%) 710(48.2) 570(44.6) 470(48.9) 1750(47.1)
District
    Kyushu (%) 753(51.2) 759(59.3) 669(69.6) 2181(58.8) <0.001
    Other than Kyushu (%) 719(48.8) 520(40.7) 292(30.4) 1531(41.2)
Years
    2007 (%) 444(30.2) 325(25.4) 237(24.7) 1006(27.1) 0.008
    2008 (%) 335(22.8) 278(21.7) 233(24.2) 846(22.8)
    2009 (%) 286(19.4) 307(24.0) 216(22.5) 809(21.8)
    2010 (%) 407(27.6) 369(28.9) 275(28.6) 1051(28.3)
Admission course
    Planned (%) 1133(77.0) 1005(78.6) 608(63.3) 2670(71.9) <0.001
    Urgent (%) 339(23.0) 350(27.4) 353(36.7) 1042(28.1)
Comorbidities
    AIDS (%) 2(0.1) 1(0.1) 0(0.0) 3(0.1) 0.514
    Cardiovascular disease (%) 75(5.1) 104(8.1) 99(10.3) 278(7.5) <0.001
    Cerebrovascular disease (%) 19(1.3) 40(3.1) 45(4.7) 104(2.8) <0.001
    Mild diabetes (%) 128(8.7) 142(11.1) 92(9.6) 362(9.8) 0.103
    Diabetes with     complication (%) 14(1.0) 8(0.6) 11(1.1) 33(0.9) 0.41
    Liver disease (%) 15(1.0) 20(1.6) 11(1.1) 46(1.2) 0.416
    Primary malignancy (%) 60(4.1) 69(5.4) 62(6.5) 191(5.1) 0.031
    Metastatic malignancy (%) 77(5.2) 53(4.1) 43(4.5) 173(4.7) 0.383
    Renal disease (%) 10(0.7) 37(2.9) 19(2.0) 66(1.8) <0.001
Other clinical events
    Sepsis (%) 78(5.3) 71(5.6) 47(4.9) 196(5.3) 0.787
    Hypercalcemia (%) 144(9.8) 150(11.7) 102(10.6) 396(10.7) 0.256
    Hypoalbminemia (%) 18(1.2) 19(1.5) 14(1.5) 51(1.4) 0.813
Treatments
    Intravenous chemotherapy
        Single agent (%) 89(6.0) 50(3.9) 31(3.2) 170(4.6) 0.002
        Multiple agent (%) 1027(69.8) 909(71.1) 501(52.1) 2437(65.7) <0.001
    Peroral chemotherapy (%) 141(9.6) 222(17.4) 163(17.0) 526(14.2) <0.001
Oppotunistic infections
    Aspergillus (%) 40(2.7) 24(1.9) 17(1.8) 81(2.2) 0.192
    Candida (%) 164(11.1) 162(12.7) 81(8.4) 407(11.0) 0.006
    Cytomegalovirus (%) 36(2.4) 49(3.8) 24(2.5) 109(2.9) 0.064
    Herpes simplex virus (%) 32(2.2) 14(1.1) 7(0.7) 53(1.4) 0.006
    Pneumocystis pneumonia (%) 212(14.4) 185(14.5) 111(11.6) 508(13.7) 0.082
    Tuberculosis (%) 36(2.4) 51(4.0) 53(5.5) 140(3.8) <0.001
    Varicella zoster virus (%) 52(3.5) 49(3.8) 17(1.8) 118(3.2) 0.014
    Other organism (%) 10(0.7) 5(0.4) 7(0.7) 22(0.6) 0.504
Outcome
    In-hospital mortality (%) 238(16.2) 287(22.4) 286(29.8) 811(21.8) <0.001
Care resource uses
    LOS median (IQR) 30(37.0) 29(41.0) 24(34.0) 28(38.0) 0.001 b
    TC median (dollar) (IQR) 11385.3(16673.0) 10467.8(16952.6) 8705.0(11391.2) 10297.9(15219.7) <0.001 b

AIDS: Acquired immunodeficiency syndrome; IQR: Interquartile range, LOS: Length of stay, TC: Total charge.

a Median age (interquartile range): 68 (15)

b Kruskal-Wallis test, all others by chi-square test