Table 4.

Cox proportional hazards regression for survival

	Bivariable analysis				Multivariable analysis
	HR	95% CI		p value	HR	95% CI		p value
NACT received
No	1.00
Yes	0.62	0.41	0.95	0.026
NACT consult
No	1.00
Yes	0.72	0.53	0.97	0.030
Location
Edmonton	1.00
Calgary	1.08	0.81	1.43	0.609
Year of diagnosis
Per year	1.02	0.92	1.14	0.706
Pathologic stage post-cystectomy
≤pT1	1.00				1.00
≥pT2	3.98	2.53	6.25	<0.001	3.74	2.43	5.77	<0.001
Sex
Male		1.00
Female	0.80	0.59	1.07	0.124
Annual surgeon case load
≤1.5	1.00			0.400
1.6–2.5	0.65	0.39	1.07
2.6–6.0	0.82	0.54	1.24
>6.0	0.86	0.57	1.30
Age
<60	1.00			0.002	1.00
60–69	1.41	0.81	2.44		1.48	0.90	2.44	0.121
70–79	1.68	1.04	2.71		1.58	1.02	2.44	0.041
≥80	2.84	1.67	4.83		2.48	1.45	4.20	0.001

NACT: neoadjuvant chemotherapy; OR: odds ratio; CI: confidence interval.