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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Neuropharmacology. 2015 Jun 1;97:149–159. doi: 10.1016/j.neuropharm.2015.05.025

Figure 6.

Figure 6

Propranolol, prazosin and duloxetine decrease binge-like ethanol intake in socially isolated animals. Propranolol dose-dependently decreased ethanol intake in the first thirty minutes of daily access among socially isolated animals (SI n = 8, a; p < 0.001), but had no effect on drinking among group housed animals (GH n = 8; p > 0.05). Similarly, prazosin significantly decreased binge-like intake in GH animals at the two highest doses administered (n = 8, b; p < 0.01), but had no effect on drinking among SI animals at any dose (n = 8; p > 0.05). Finally, duloxetine decreased binge-like intake in SI animals (n = 13, c; p < 0.001), but had no effect on drinking among GH animals (n = 12; p > 0.05).