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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: JAMA Ophthalmol. 2015 Aug 1;133(8):915–923. doi: 10.1001/jamaophthalmol.2015.1440

Table 2.

Study Population Use of Diabetes Medicationsa

Diabetes Medication Type Diabetic Patients, No. (%) P Value Based
on t Test
All Diabetic
Patients, No. (%)
Did Not Develop OAG Developed OAG
Sulfonylureas 44 659 (31.0) 1846 (31.3) .58 46 505 (31.0)
Metformin hydrochloride 57 993 (40.2) 2221 (37.7) <.001 60 214 (40.1)
Thiazolidinediones 34 265 (23.8) 1442 (24.5) .22 35 707 (23.8)
Meglitinides 3510 (2.4) 153 (2.6) .43 3663 (2.4)
Insulin 32 704 (22.7) 1244 (21.1) .005 33 948 (22.6)
Othersb 10 536 (7.3) 283 (4.8) <.001 10 819 (7.2)

Abbreviation: OAG, open-angle glaucoma.

a

Some enrollees were prescribed more than 1 medication class.

b

Exenatide, sitagliptin, or pramlintide.