Structural change, superoxide generation and contraction of afferent arterioles from mice with tamoxifen inducible SOD-3 −/− after vehicle (open boxes and open circles), inducible SOD-3 after tamoxifen (cross hatched boxes and open triangles) or stable SOD-3 −/− (solid boxes and solid circles). Compared to arterioles from inducible SOD-3 −/− after vehicle: *, P<0.05; **, P<0.01; ***, P<0.005.