Table 2.
Parameter | ART-treated optimal responders | Healthy-HIV-negative people | p-Value |
---|---|---|---|
CD4 T-cell proliferation | |||
SEB antigen, median % | 6.32 | 5.84 | 0.971 |
PPD antigen, median % | 0.74 | 4.430 | 0.016 |
Pneumococcal polysaccharide antigen | 0.74 | 4.43 | 0.016 |
CMV antigen, median % | 2.650 | 2.050 | 0.480 |
Cytokine production after stimulation with SEB antigen | |||
IL-2, median % | 0 | 0.74 | 0.0002 |
IL-4, median % | 2.50 | 2.57 | 0.528 |
IFN-gamma, median % | 2.15 | 3.72 | 0.891 |
ART, antiretroviral therapy, SEB, Staphylococcal enterotoxin B, PPD, purified protein derivative, CMV, cytomegalovirus, IL-2, interleukin-2, IL-4, Interleukin-4, IFN-γ, interferon gamma.