Table 3.
Stability of cannabinoids at low (150 pg/pad), medium (750 pg/pad), and high (7500 pg/pad) concentrations.a
| Stability condition | THCCOOH | THC | CBN |
|---|---|---|---|
| 1 h Room temperature low | −1.8% | −10.9% | −9.8% |
| 1 h Room temperature medium | 6.7% | −5.9% | −5.4% |
| 1 h Room temperature high | 10.9% | −5.2% | −6.5% |
| 8 h Room temperature low | 8.9% | 3.8% | 5.3% |
| 8 h Room temperature medium | −7.4% | −2.1% | −3.4% |
| 8 h Room temperature high | −4.8% | −2.0% | −3.9% |
| 72 h 4 °C low | 14.0% | 2.4% | −4.2% |
| 72 h 4 °C medium | 4.2% | −1.4% | −3.4% |
| 72 h 4 °C high | 7.6% | 0.4% | 1.1% |
| 3 Freeze/thaw cycles low | 10.2% | −1.6% | −4.7% |
| 3 Freeze/thaw cycles medium | 5.9% | −2.6% | −3.7% |
| 3 Freeze/thaw cycles high | 7.4% | −0.7% | −2.5% |
| 1 week −20 °C low | 10.4% | −3.6% | −4.9% |
| 1 week −20 °C high | 0.8% | −7.8% | −5.6% |
| 1 month −20 °C low | −14.9% | −1.1% | −5.8% |
| 1 month −20 °C high | 13.7% | −5.8% | −3.6% |
| 3 month −20 °C low | −3.1% | 1.6% | −4.7% |
| 3 month −20 °C high | 1.0% | −0.8% | −1.6% |
| 6 month −20 °C low | −17.3% | −18.2% | −18.0% |
| 6 month −20 °C high | −10.8% | −17.3% | −13.3% |
| 72 h 4 °C autosampler low | −7.0% | 0.0% | −1.7% |
| 72 h 4 °C autosampler medium | −0.5% | 0.3% | 3.5% |
| 72 h 4 °C autosampler high | −2.2% | −2.2% | −1.2% |
a
Mean percentage difference (n = 3); positive values indicate percentage increase from original QC concentrations.