Table 1.
Condition | Incidence in U.S. (annual) | Mortality Rates (%) | Functional Independence at 3-12 months (%) | |
---|---|---|---|---|
In-Hospital | 30-Day | |||
Traumatic Brain Injury | 2,500,000 [97] | 7.5% [98] | 21% [99] | 25-32%* [100-102] |
Ischemic Stroke | 795,000 [97] | 4.3-70% [98, 103] | 16-23%[104, 105] | 50% [106-108] |
Anoxic Brain Injury | 424,000 out-of-hospital cardiac arrests [109] | 52-90%^ [98, 110] | 25-40%** [111, 112] | 48-55%** [111, 112] |
Status Epilepticus^^ | 200,000 [113] | 14-50% [114, 115] | 19-65% [116-118] | 42% [119] |
Intracerebral Hemorrhage | 63,000 [120] | 30% [98] | 34-50% [120-123] | 12-39% [123] |
Subarachnoid Hemorrhage | 25,000 [124] | 20-26% [98, 124-127] | 45% [98, 124-127] | 16-55% [128, 129] |
Among patients with severe traumatic brain injury
Overall 90% mortality including those who do not survive to hospital admission [109]
Among patients who underwent targeted temperature management. Mortality rates are higher and functional outcome worse in patients with PEA/asystole arrest compared to Vfib/Vtach arrest.
Patients with refractory status epilepticus (continued seizures after two anti-epileptic drugs have been administered) have higher mortality rates and worse functional outcomes.