Table 1.
Immunohistochemical profile in lung squamous cell carcinomas confirmed with immunohistochemistry (n = 449)
| Marker | Positive | Distribution
|
Intensity
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Focal | Diffuse | Weak | Moderate | Strong | ||||||||
| N | % | N | % | N | % | N | % | N | % | N | % | |
| p40 | 449 | 100% | 13 | 3% | 436 | 97% | 3 | 1% | 36 | 8% | 410 | 91% |
| p63* | 446 | 100% | 14 | 3% | 432 | 97% | 8 | 2% | 34 | 8% | 404 | 91% |
| TTF-1 8G7G3/1 | 0 | 0% | 0 | 0% | 0 | 0% | 0 | 0% | 0 | 0% | 0 | 0% |
| TTF-1 SPT24** | 27 | 6% | 19 | 70% | 8 | 30% | 17 | 63% | 7 | 26% | 3 | 11% |
| Napsin A** | 0 | 0% | 0 | 0% | 0 | 0% | 0 | 0% | 0 | 0% | 0 | 0% |
| Chromogranin A | 45 | 10% | 41 | 91% | 4 | 9% | 40 | 89% | 4 | 9% | 1 | 2% |
| Synaptophysin** | 17 | 4% | 16 | 94% | 1 | 6% | 11 | 65% | 5 | 29% | 1 | 6% |
| CD56 | 70 | 16% | 36 | 51% | 34 | 49% | 59 | 84% | 7 | 10% | 4 | 6% |
*
No tissue microarray core in 3 cases.
**
No tissue microarray core in 1 case.