. Author manuscript; available in PMC: 2016 Sep 1.

Published in final edited form as: Am J Surg Pathol. 2015 Sep;39(9):1170–1180. doi: 10.1097/PAS.0000000000000439

Table 3.

Immunohistochemical profile in tumors reclassified into other histology from squamous cell carcinoma (n=30)

Histology/Marker	Positive		Distribution				Intensity
	Positive		Focal		Diffuse		Weak		Moderate		Strong
	N	(%)	N	(%)	N	(%)	N	(%)	N	(%)	N	(%)
Adenocarcinoma (n=20)
p40	3	15%	3	100%	0	0%	1	33%	2	67%	0	0%
p63	8	40%	7	88%	1	13%	4	50%	4	50%	0	0%
TTF-1 (8G7G3/1)	13	65%	8	62%	5	38%	6	46%	2	15%	5	38%
TTF-1 (SPT24)	20	100%	4	20%	16	80%	0	0%	3	15%	17	85%
Napsin A	13	65%	3	23%	10	77%	2	15%	4	31%	7	54%
Chromogranin A	3	15%	3	100%	0	0%	3	100%	0	0%	0	0%
Synaptophysin	2	10%	2	100%	0	0%	2	100%	0	0%	0	0%
CD56	0	0%	0	0%	0	0%	0	0%	0	0%	0	0%

Neuroendocrine carcinoma (n=6)
p40	1	17%	0	0%	1	100%	0	0%	0	0%	1	100%
p63	3	50%	2	67%	1	33%	2	67%	0	0%	1	33%
TTF-1 (8G7G3/1)	2	33%	2	100%	0	0%	2	100%	0	0%	0	0%
TTF-1 (SPT24)	3	50%	1	33%	2	67%	1	33%	0	0%	2	67%
Napsin A	1	17%	1	100%	0	0%	1	100%	0	0%	0	0%
Chromogranin A	3	50%	3	100%	0	0%	1	33%	2	67%	0	0%
Synaptophysin	3	50%	2	67%	1	33%	1	33%	2	67%	0	0%
CD56	5	83%	0	0%	5	100%	2	40%	2	40%	1	20%

Large cell carcinoma (n=4)
p40	0	0%	0	0%	0	0%	0	0%	0	0%	0	0%
p63	1	25%	1	100%	0	0%	0	0%	1	100%	0	0%
TTF-1 (8G7G3/1)	0	0%	0	0%	0	0%	0	0%	0	0%	0	0%
TTF-1 (SPT24)	0	0%	0	0%	0	0%	0	0%	0	0%	0	0%
Napsin A	0	0%	0	0%	0	0%	0	0%	0	0%	0	0%
Chromogranin A	1	25%	1	100%	0	0%	1	100%	0	0%	0	0%
Synaptophysin	0	0%	0	0%	0	0%	0	0%	0	0%	0	0%
CD56	0	0%	0	0%	0	0%	0	0%	0	0%	0	0%