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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Shock. 2015 Sep;44(3):200–208. doi: 10.1097/SHK.0000000000000406

Figure 3.

Figure 3

Serum metabolites associated with free hemoglobin levels. (A) Valine, a branched chain amino acid; (B) glutamate, which is integral in glucose metabolism and amino acid transport and utilization, particularly in skeletal muscle; (C) phenylalanine, which is transported by RBC; (D) leucine, a branched chain amino acid; (E) creatine phosphate (see text); (F) alanine, which is transported by RBC; (G) isoleucine, a branched chain amino acid; and (H) 2-hydroxybutyrate, a by-product in the pathway of glutathione synthesis were all associated with free Hgb levels in serum. Metabolite and free Hgb levels were available from 19 of 20 serum samples obtained from healthy subjects. The Spearman correlation coefficients (ρ) and the associated p values are reported.