Table 1.
Effects of lisinopril and fosinopril on the transfer latencies on 1st day and 2nd day in elevated plus maze test.
| Treatment | Transfer latency on the 1st day (sec) |
Transfer latency on 2nd day after 24 h (sec) |
|---|---|---|
| Control | 57.50 ± 4.32∗∗ | 35.50 ± 2.15∗∗,b |
| Saline control | 61.00 ± 3.20∗∗ | 37.90 ± 2.81∗∗ |
| Scopolamine | 92.17 ± 5.57b | 94.00 ± 3.55b |
| Lisinopril (0.225 mg/kg) + scopolamine | 83.33 ± 3.81b | 75.61 ± 2.75b |
| Lisinopril (0.45 mg/kg) + scopolamine | 76.16 ± 5.74∗,a | 55.17 ± 3.04∗∗,a |
| Fosinopril (0.90 mg/kg) + scopolamine | 85.33 ± 3.56b | 75.67 ± 5.16b |
| Fosinopril (1.80 mg/kg) + scopolamine | 73.50 ± 3.34∗∗,a | 53.00 ± 3.67∗∗ |
Comparisons between control, scopolamine, lisinopril, and fosinopril treated groups in the elevated plus maze test. Values are mean ± SE, ∗versus scopolamine (p < 0.05), ∗∗versus scopolamine (p < 0.001), aversus control (p < 0.05), and bversus control (p < 0.001).