Skip to main content
. 2015 Aug 2;2015:521718. doi: 10.1155/2015/521718

Table 2.

Effects of lisinopril and fosinopril on the exploratory behaviour of scopolamine-induced amnesic rats in passive avoidance test.

Treatment Exploration trial (day 1) Exploration trial (day 2) Exploration trial (day 3)
Control 19.3 ± 0.95∗∗ 17.16 ± 1.54∗∗ 12.67 ± 1.31∗∗
Saline control 20.6 ± 1.28∗∗ 16.00 ± 2.71∗∗ 14.10 ± 1.92∗∗
Scopolamine 37.3 ± 2.55b 33.5 ± 1.88b 30.67 ± 1.85b
Lisinopril (0.225 mg/kg) + scopolamine 39.5 ± 2.91b 38.22 ± 1.03b 27.50 ± 2.46b
Lisinopril (0.45 mg/kg) + scopolamine 34.75 ± 1.88b 31.00 ± 2.71b 25.21 ± 1.18b,
Fosinopril (0.90 mg/kg) + scopolamine 35.75 ± 2.78b 36.0 ± 2.92b 25.50 ± 1.08b,
Fosinopril (1.80 mg/kg) + scopolamine 34.00 ± 3.02b 28.75 ± 2.45a, 19.75 ± 1.26a,

Comparison between control, scopolamine, lisinopril, and fosinopril during the exploration trials in passive avoidance test. Values are mean ± SE, versus scopolamine (p < 0.05), ∗∗versus scopolamine (p < 0.001), aversus control (p < 0.05), and bversus control (p < 0.001).