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. 2015 Aug 2;2015:521718. doi: 10.1155/2015/521718

Table 3.

Effects of lisinopril and fosinopril on memory retention behaviour of scopolamine-induced amnesic rats in passive avoidance test.

Treatment Latency to enter the dark compartment (sec) 24 h after receiving foot shock Total time spent in light compartment (sec) 24 h after receiving foot shock
Control 51.83 ± 2.71∗∗ 114.50 ± 3.87∗∗
Saline control 49.29 ± 2.21∗∗ 109.78 ± 2.55∗∗
Scopolamine 14.83 ± 1.05b 57.33 ± 4.23b
Lisinopril (0.225 mg/kg) + scopolamine 25.68 ± 2.34b 63.00 ± 5.45b
Lisinopril (0.45 mg/kg) + scopolamine 27.81 ± 4.78b 73.67 ± 2.24a
Fosinopril (0.90 mg/kg) + scopolamine 29.83 ± 4.09,b 88.66 ± 8.59b
Fosinopril (1.80 mg/kg) + scopolamine 36.33 ± 2.89∗∗,a 98.17 ± 3.54∗∗

Comparisons between control, scopolamine, lisinopril, and fosinopril during the retention trial in passive avoidance test. Values are mean ± SE, versus scopolamine (p < 0.05), ∗∗versus scopolamine (p < 0.001), aversus control (p < 0.05), and bversus control (p < 0.001).