Table 3.
Treatment | Latency to enter the dark compartment (sec) 24 h after receiving foot shock | Total time spent in light compartment (sec) 24 h after receiving foot shock |
---|---|---|
Control | 51.83 ± 2.71∗∗ | 114.50 ± 3.87∗∗ |
Saline control | 49.29 ± 2.21∗∗ | 109.78 ± 2.55∗∗ |
Scopolamine | 14.83 ± 1.05b | 57.33 ± 4.23b |
Lisinopril (0.225 mg/kg) + scopolamine | 25.68 ± 2.34b | 63.00 ± 5.45b |
Lisinopril (0.45 mg/kg) + scopolamine | 27.81 ± 4.78b | 73.67 ± 2.24a |
Fosinopril (0.90 mg/kg) + scopolamine | 29.83 ± 4.09∗,b | 88.66 ± 8.59b |
Fosinopril (1.80 mg/kg) + scopolamine | 36.33 ± 2.89∗∗,a | 98.17 ± 3.54∗∗ |
Comparisons between control, scopolamine, lisinopril, and fosinopril during the retention trial in passive avoidance test. Values are mean ± SE, ∗versus scopolamine (p < 0.05), ∗∗versus scopolamine (p < 0.001), aversus control (p < 0.05), and bversus control (p < 0.001).