Table 5.
Effects of lisinopril and fosinopril in the probe trial on day 5 of Morris water maze test.
| Treatment | Latency to enter the target quadrant (sec) | Total time spent in target quadrant (sec) |
|---|---|---|
| Control | 14.59 ± 1.54∗∗ | 26.11 ± 0.54∗∗ |
| Saline control | 17.11 ± 1.62∗∗ | 29.20 ± 1.66∗∗ |
| Scopolamine | 27.48 ± 2.00b | 12.58 ± 0.42b |
| Lisinopril (0.225 mg/kg) + scopolamine | 23.90 ± 1.37b | 12.28 ± 0.37b |
| Lisinopril (0.45 mg/kg) + scopolamine | 22.83 ± 1.96b | 14.75 ± 0.96b |
| Fosinopril (0.90 mg/kg) + scopolamine | 22.29 ± 1.91b | 14.37 ± 0.91b |
| Fosinopril (1.80 mg/kg) + scopolamine | 20.18 ± 0.85∗,a | 19.25 ± 1.85∗,a |
Comparison between control, scopolamine, lisinopril, and fosinopril treated groups in the probe trial of Morris water maze test in which no platform was present. Values are mean ± SE, ∗versus scopolamine (p < 0.05), ∗∗versus scopolamine (p < 0.001), aversus control (p < 0.05), and bversus control (p < 0.001).