Table 1.
Genotype and allele frequency distributions in patients (n = 90) with idiopathic scoliosis (IS) and healthy controls (n = 180).
| Gene, polymorphism |
Genotype, allele |
Cases n, % |
Controls n, % |
p value |
|---|---|---|---|---|
|
Leptin
rs7799039 |
AA | 25 (27.8) | 55 (30.6) | 0.64 |
| AG | 42 (46.7) | 88 (48.9) | ||
| GG | 23 (25.6) | 37 (20.6) | ||
| A | 92 (51.1) | 198 (55.0) | 0.39 | |
| G | 88 (48.9) | 162 (45.0) | ||
|
| ||||
|
BMP4
rs4898820 |
TT | 27 (30.0) | 46 (25.6) | 0.74 |
| GT | 46 (51.1) | 99 (55.0) | ||
| GG | 17 (18.9) | 35 (19.4) | ||
| T | 100 (55.6) | 191 (53.1) | 0.58 | |
| G | 80 (44.4) | 169 (46.9) | ||
A p-value < 0.05 was considered to be statistically significant. BMP4 indicates bone morphogenetic protein 4.