Table 2.
Cardiac risk factors present in 100 men prior to receiving androgen deprivation therapy.
| Risk factor | All patients (n = 100) | High FRS (n = 49) | Intermediate FRS (n = 25) | Low FRS (n = 1) |
|---|---|---|---|---|
| Hypertension | 58 (58%) | 28 (57%) | 7 (28%) | 0 |
| Diabetes mellitus or IGT | 22 (22%) | 11 (22%) | 6 (24%) | 0 |
| Cigarette smoking | ||||
| Never | 46 (46%) | 22 (45%) | 14 (56%) | 1 (1%) |
| Current | 6 (6%) | 3 (6%) | 2 (8%) | 0 |
| Quit < 5 years ago | 3 (3%) | 1 (2%) | 1 (4%) | 0 |
| Quit > 5 years ago | 44 (44%) | 23 (47%) | 7 (28%) | 0 |
| Family history of CAD | 10 (10%) | 2 (4%) | 0 | 0 |
| Dyslipidemia | 51 (51%) | 19 (39%) | 10 (40%) | 0 |
| Chronic kidney disease (GFR < 60 mL/min/1.73 m2) | 10 (10%) | 6 (12%) | 1 (4%) | 0 |
| Medication class | ||||
| ASA | 33 (33%) | 12 (24%) | 2 (8%) | 0 |
| Clopidogrel | 1 (1%) | 0 | 0 | 0 |
| Warfarin | 3 (3%) | 3 (6%) | 0 | 0 |
| ACE inhibitor | 32 (32%) | 16 (33%) | 2 (8%) | 0 |
| ARB | 16 (16%) | 8 (16%) | 2 (8%) | 0 |
| Beta blocker | 17 (17%) | 7 (14%) | 1 (4%) | 0 |
| Other antihypertensives | 31 (31%) | 15 (31%) | 4 (16%) | 0 |
| Statin | 40 (40%) | 13 (27%) | 6 (24%) | 0 |
| Nitroglycerin | 1 (1%) | 0 | 0 | 0 |
| Insulin | 4 (4%) | 3 (6%) | 0 | 0 |
ACE: angiotensin converting enzyme; ARB: angiotensin receptor blocker; ASA: acetylsalicylic acid; CAD: coronary artery disease; FRS: Framingham risk score; GFR: glomerular filtration rate; IGT: impaired glucose tolerance.