Skip to main content
. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Drug Alcohol Depend. 2015 Jul 17;154:264–270. doi: 10.1016/j.drugalcdep.2015.07.009

Table 2.

Functional Magnetic Resonance Imaging Results

Vol (μL)/#Voxels x y z Hem Regions Within Cluster BA Effect Size PSU vs. DSU Effect Size PSU vs. CTL
Group Main Effect: PSU ↑ DSU and/or CTL across trials
1536/24 37 19 14 R Anterior Insula1 13 1.39 1.57
832/13 −41 16 12 L IFG1 44 1.47 0.97
768/12 47 10 16 R IFG1 44 ns 1.35
640/10 46 −44 30 R Supramarginal Gyrus1 40 ns 1.49
640/10 10 16 61 R SFG2 6 1.19 0.97
Group by Condition Interaction: PSU ↑ DSU and/or CTL during Soft Touch condition
1344/21 −45 8 8 L PCG/Middle Insula1 13 1.48 0.96‡
1152/18 51 −51 13 R STG1 22 1.09 0.85
960/15 42 15 8 R PCG/Middle Insula1 13 0.88† 1.16

Note:

1

Bonferroni corrected post-hoc comparisons p < .05.

2

Games-Howell corrected post-hoc comparisons p < .05.

†

Did not achieve significance (.05 < p < .10) when n=3 PSU and n=1 DSU with alcohol dependence were removed from analyses.

‡

Did not achieve significance (.05 < p < .10) when n=3 PSU with marijuana dependence were removed from analyses.

ns = non-significant. PSU = Problem Stimulant Users. DSU = Desisted Stimulant Users. CTL = Healthy Comparison Subjects. Vol = Volume. Hem = Hemisphere. L = Left Hemisphere. R = Right Hemisphere. BA = Brodmann Area. Effect Size = Cohen’s d. Coordinates reflect center of mass. SFG = superior frontal gyrus. IFG = inferior frontal gyrus. PCG = precentral gyrus. STG = superior temporal gyrus. No significant differences emerged between PSU and the other two groups for the anticipation condition.