Fig. 3.
Image segmentation. In the signal threshold segmentation (a) and corresponding bright vs. dark scatter plot representation (b) the signal threshold is set according to the 35% criterion value, Z = 90.4 in this example. Voxel samples exhibiting difference signal above and below the threshold appear red and yellow, respectively, with the solid line indicating the Z = 90.4 contour. In the cluster association segmentation (c) and corresponding bright vs dark scatter plot representation (d), yellow and red indicate voxel samples exhibiting a posterior probability (with respect to the perfusion component) above and below p = 0.5, respectively. Dashed lines indicate the Z = 0 contour with voxel samples exhibiting a negative difference signal value indicated in black (all panels). (e) The corresponding ASL difference image (color represents variation about the image mean scaled in units of standard deviation) has been included for comparison.