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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Prog Biophys Mol Biol. 2015 Apr 14;118(3):153–160. doi: 10.1016/j.pbiomolbio.2015.04.001

Figure 7. The DCC N-terminal horseshoe configuration.

Figure 7

The Ribbon diagram of the crystal structure depicting the four N-terminal Immunoglobulin (Ig) domains of DCC (colored in gold). The folding of the four domains results in a horseshoe configuration, with the first two domains D1 and D2 bending over to contact the proceeding two domains, D4 and D3. This configuration was demonstrated to be functionally relevant for netrin-1 mediated axonal attraction.