(A) Cytoscape enrichment map of significant genesets distinguishing Grade II versus myxopapillary spinal ependymomas identified by Gene Set Enrichment Analysis (GSEA) and visualized in Cytoscape. A statistical significance cutoff of p < 0.01 and FDR < 0.25 was used for the pathway analysis
(B) Donut plot demonstrating significant over-representation of pathways and biological processes in involving hypoxia signaling and cellular metabolism in myxopapillary spinal ependymoma
(C) Single sample GSEA demonstrating subgroup-specific over-representation of pathways and biological processes involving cellular metabolism and hypoxia signaling. Bar graph of the ages of patients is shown in the lower panel.