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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Microvasc Res. 2015 Jun 27;101:72–81. doi: 10.1016/j.mvr.2015.06.006

Figure 1. Co-culture of ECFC with human platelet lysate (HPL) diminishes apoptosis of ECFC in 3D collagen matrices in vitro.

Figure 1

Figure 1

(a) The Annexin V−/PI− viable population of co-cultured ECFC with HPL was significantly higher on day 1 and 3 compared to ECFC alone culture. N=3 *P < 0.05. (b) Representative images of vascular structures of ECFC cultured with or without HPL in collagen matrices on day 1 and 3 (white arrows indicate the structures and small boxes indicates representative counted structures). Scale bar represents 0.05µm. Co-culture of ECFC with HPL resulted in a significant increase in (c) the average number of vascular structures per collagen matrix surface area and (d) total luminal area of vascular structures per matrix surface area (mm2) compared to controls. N=10 each group *P < 0.05, **P<0.001 or ***P<0.0001.