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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Microvasc Res. 2015 Jun 27;101:72–81. doi: 10.1016/j.mvr.2015.06.006

Figure 5. Inhibition of pro-survival molecules affects protein expression of molecules involved in the apoptotic/cell survival signaling in 3D collagen matrices.

Figure 5

Figure 5

(a) Representative immunoblots of inhibitor treatment of ECFC or ECFC with HPL in 3D collagen matrices (DMSO as vehicle control, Akt1 inhibitor, 2µm, Akt2 inhibitor 2µm and Bcl-xL inhibitor 20nM). Lower panels show quantification of repeated experiments of the inhibitor treatment ECFC alone (b) and ECFC with HPL (c) in 3D collagen matrix on day 1 after culture (protein expression levels were normalized using GAPDH). N=2 each group *P < 0.05, **P<0.001 or ***P<0.0001.