Table 2.
Multivariate analysis of recipient KIR Ligands for AML only
Recipient KIR Ligands | All present | ≥ 1 absent | |||
---|---|---|---|---|---|
N | Reference | N | HR (95% CI) | P-value | |
Overall survivala | 217 | 1.00 | 395 | 1.04 (0.85–1.28) | 0.69 |
DFSb | 217 | 1.00 | 395 | 0.93 (0.75–1.15) | 0.49 |
TRMc | 213 | 1.00 | 390 | 1.43 (1.01–2.01) | 0.04 |
Relapsed | 215 | 1.00 | 394 | 0.81 (0.62–1.05) | 0.11 |
aGVHD II–IVe | 217 | 1.00 | 392 | 1.22 (0.97–1.53) | 0.09 |
aGVHD III–IVf | 217 | 1.00 | 393 | 1.63 (1.16–2.28) | 0.005 |
cGVHDg | 208 | 1.00 | 387 | 1.07 (0.84–1.37) | 0.59 |
Adjusted for disease stage, donor/recipient CMV matching, GVHD prophylaxis, recipient race/ethnicity and stratified by graft type.
Adjusted for disease stage and stratified by graft type, donor/recipient CMV matching and Karnofsky score.
Adjusted for recipient race/ethnicity, donor/recipient sex matching, conditioning regimen, GVHD prophylaxis, time from diagnosis to transplant and stratified by graft type.
Adjusted for disease stage and time from diagnosis to transplant and stratified by conditioning regimen and Karnofsky score.
Adjusted for graft type, GVHD prophylaxis, recipient race and stratified by use of CAMPATH.
Adjusted for HLA matching, recipient race/ethnicity, GVHD prophylaxis and Karnofsky score.
Adjusted for in-vivo T-cell depletion, conditioning regimen, GVHD prophylaxis and stratified by recipient CMV status.