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. 2015 Jun 12;309(4):H634–H645. doi: 10.1152/ajpheart.00207.2015

Fig. 2.

Fig. 2.

Mean arterial pressure (MAP; A–D) and heart rate (HR; E–H) responses to 60 min of restraint stress (A, B, E, and F) and 15 min of water stress (C, D, G, and H) in GFP (solid squares or bars)- and MIF-treated (open circles or bars) Sprague-Dawley rats. Stress begins at time = 0. Bar graphs represent values averaged for the durations of stress and recovery. There were no significant effects of MIF on the stress responses in these rats. MIF treatment also had no significant effect on baseline values for MAP and HR, and data are expressed as changes from baseline values. Baseline MAP and HR values recorded before restraint stress were 95 ± 4 mmHg and 314 ± 7 beats/min in GFP (n = 6) and 100 ± 2 mmHg and 309 ± 6 beats/min in MIF rats (n = 8). Baseline MAP and HR values recorded before water stress were 95 ± 2 mmHg and 305 ± 8 beats/min in GFP (n = 6) and 99 ± 2 mmHg and 299 ± 7 beats/min in MIF rats (n = 8).