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. 2015 Jun 12;309(4):H634–H645. doi: 10.1152/ajpheart.00207.2015

Fig. 4.

Fig. 4.

MAP (A–D) and HR (E–H) responses to 60 min of restraint stress (A, B, E, and F) and 15 min of water stress (C, D, G, and H) in GFP (solid squares or bars)- and MIF-treated (open circles or bars) SHRs. Stress begins at time = 0. Data are expressed as changes from baseline values, and bar graphs represent values averaged for the durations of stress and recovery. MIF treatment significantly attenuated the arterial pressure response to restraint stress during both the stress and recovery periods but had no significant effect on baseline values for MAP and HR. Baseline MAP and HR values recorded before restraint stress were 95 ± 4 mmHg and 314 ± 7 beats/min in GFP (n = 8) and 100 ± 2 mmHg and 309 ± 6 beats/min in MIF rats (n = 7). Baseline MAP and HR values recorded before water stress were 95 ± 2 mmHg and 305 ± 8 beats/min in GFP (n = 9) and 99 ± 2 mmHg and 299 ± 7 beats/min in MIF rats (n = 8). *P < 0.05 MIF vs. GFP.