A: average baseline plasma corticosterone concentration in all GFP (n = 15)- and MIF (n = 16)-treated rats. B: plasma corticosterone concentration at baseline (time 0) and after 10, 15, 30, 45 and 60 min of restraint stress (n = 9 per group) or in time control experiments (n = 5–6 per group). C: average change from baseline in plasma corticosterone in response to restraint stress and during time control experiments calculated from data in B. D: plasma corticosterone concentration at baseline (time 0) and after 10, 15, 30, 45, and 60 min of water stress (n = 7 for GFP and 9 for MIF treatment.). *P < 0.05 MIF vs. GFP.