Figure 2.

The effects ofmatrine on cell-cycle arrest and apoptosis in Hep G2 cells. A. The DNA fragmentation of Hep G2 induced by matrine, as determined by electrophoresis assay at 48 h with various concentrations of matrine treatment. B. Quantitative evaluations of terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick endlabeling (TUNEL) assay by flow cytometry. C. The distribution of cellcycle in matrine-treated cells. Each value is the mean ± SD of three determinations. *P < 0.05 represents significant differences between control and matrine-treated cells.