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. 2015 Jun 15;8(6):10036–10039.

Table 5.

Interaction analysis between OPRM1 and COMT genes

Genotype combinations N Pain threshold Pain tolerance
AA-VV 74 2.3±0.9 5.5±1.3
AA-VM 44 2.2±1.0 5.4±1.2
AA-MM 26 2.0±1.1 5.0±1.1
AG-VV 51 2.2±0.9 5.3±1.2
AG-VM 49 1.7±0.9 4.5±1.3*
AG-MM 14 1.6±0.9* 4.4±1.2*
GG-VV 13 2.0±0.9 4.8±1.6
GG-VM 22 1.6±0.8* 4.4±1.2*
GG-MM 7 1.5±0.8* 4.3±1.2*
*

P < 0.05, compared to AA-VV group.