Table 2.
Methods of solvent configuration in each group
| Groups | Methods | |
|---|---|---|
| Group A | Core | 10% PLLA + 0.4 ml DI emulsification |
| Shell | 10% PLGA | |
| Group B | Core (hydrophobic) | 10% PLLA (10 mL) + 50 mg RFP + 50 mg PZA) |
| Shell (hydrophilic) | 10% PLGA (10 mL + 0.4 ml DI + 50 mg INH + 50 mg EMBH emulsification | |
| Group C | Core (hydrophilic) | 10% PLLA (10 mL) + (0.4 ml DI + 50 mg INH + 50 mg EMBH) emulsification |
| Shell (hydrophobic) | 10% PLGA (10 mL) + (50 mg RFP + 50 mg PZA) |
Note: DI, deionized water; RFP, rifampicin; PZA, pyrazinamide; INH, isoniazid; EMBH, ethambutol hydrochloride.