Table 3.
This is a summary of the effects of the treatments relative to balanced mixture (BAL)
| Serum analytes | Brain serotonergic system | Brain dopaminergic system | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Treatment | TRP | 5-HT | TYR | Trp | 5-HT | 5-HIAA | TYR | DA | DOPAC | HVA |
| ATD | ↓↓ | = | = | ↓↓ | ↓ | ↓↓ | = | = | = | ↓ (HPC, CPu) |
| SATD | ↓↓ | = | = | ↓↓ | ↓ | ↓↓ | = | = | ↓ (Amyg) | ↓ (HPC, NAcc, CPu) |
FC=frontal cortex; HPC=hippocampus; Amyg=amygdala; CPu=caudate putamen.
For effects that were observed only in certain regions, the affected region is indicated in parenthesis.
↓↓ indicates a 35–60% depletion; ↓ indicates a 20–34% depletion;=indicates no effects.