Table 1.
Timing | Within one week of a known clinical insult or new or worsening respiratory symptoms. |
| |
Chest imaging | Bilateral opacities not fully explained by effusions, lobar/lung collapse, or nodules. |
| |
Origin of oedema | Respiratory failure not fully explained by cardiac failure or fluid overload. Need for objective assessment (e.g., echocardiography) to exclude hydrostatic oedema if no risk factors are present. |
| |
Oxygenation | |
Mild | 200 mmHg < PaO2/FIO2 ≤ 300 mmHg with PEEP or CPAP ≥ 5 cmH2O |
Moderate | 100 mmHg < PaO2/FIO2 ≤ 200 mmHg with PEEP ≥ 5 cmH2O |
Severe | PaO2/FIO2 ≤ 100 mmHg with PEEP ≥ 5 cmH2O |
PaO2: partial pressure of arterial oxygen; FIO2: fraction of inspired oxygen; PEEP: positive end expiratory pressure; CPAP: continuous positive airway pressure.