Figure 2.
Enzymatic generation of electrophilic ketoderivatives of EPA (a), DHA (b), and DPA (c). Cox-2, cyclooxygenase-2; PGDS, prostaglandin D synthase; 5-LO, 5-lipoxygenase; 5-HEDH, 5-hydroxyeicosanoid dehydrogenase; deH, cellular dehydrogenases.
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