Table 2. Summary of Participating PGC–PTSD Groups.
| Principal investigator | Sample name | Cases | Controls | Total | Ancestry | Illumina platform |
|---|---|---|---|---|---|---|
| Previously genotyped samples | ||||||
| Ressler, Kerry | Grady trauma project | 1503 | 3249 | 4752 | AA—Mixed | 1M Omni-Quad |
| Aiello, Allison | Detroit Neighborhood Health Study | 192 | 620 | 812 | AA | OmniExpress |
| Gelernter, Joel | Genetics of substance dependence | 818 | 4633 | 5451 | 60% EA | OmniQuad |
| Nievergelt, C. | Marine Resilience Study | 538 | 3477 | 4015 | EA 60% | OmniExpressExome |
| Bierut, Laura | Family Study of Cocaine Dependent | 471 | 3568 | 4039 | Mixed | 1M Beadchip |
| Miller, Mark | Boston-VA | 600 | 500 | 1100 | Mixed | Omni 2.5M |
| Stein, Murray | Army STARRS | 4500 | 15500 | 20000 | Mixed | OmniExpressExomeC |
| Beckham, Jean | MIRECC | 1156 | 1156 | 2312 | Mixed | 650/1M-Duo/Omni2.5 |
| Ressler, Kerry | Grady trauma project | 497 | 1751 | 2248 | AA—Mixed | 1M Omni-Quad |
| Stein, Murray | VA Cooperative Study | 10000 | 10000 | 20000 | Mixed | OmniExpressExomeC |
| DeLisi, Lynn | UCSD VA | 1000 | 1000 | 2000 | Mixed | |
| Smith, Nicholas | VET Study | 492 | 377 | 869 | Mixed | |
| Hollegaard, Mads | Danish Blood Spot Cohort | 500 | 2500 | 3000 | EA | |
| Subtotal | 22267 | 48331 | 70650 | |||
| Samples with funded genotyping | ||||||
| Koenen, Karestan | Nurses Health Study II | 680 | 700 | 1380 | EA | PsychChip |
| Liberzon, Israel | Ohio national Guard Study | 170 | 200 | 370 | EA | PsychChip |
| Lyons, Michael | Vietnam Era Twin Registry | 350 | 350 | 700 | EA | PsychChip |
| Ressler, Kerry / Dan Stein | Civilian South African Cohort | 200 | 400 | 600 | S. African | PsychChip |
| Vermetten, Eric | Military Research (PRISMO) | 35 | 965 | 1000 | EA | PsychChip |
| Bryant, Richard | Australian Injury Vulnerability Study | 205 | 796 | 1001 | EA | PyschChip |
| Ressler, Kerry | Predictive Biomarkers Project | 200 | 400 | 600 | 80% AA | PsychChip |
| Subtotal | 1840 | 3811 | 5651 | |||
| Additional samples identified for future genotyping once funding is obtained | ||||||
| Ressler, Kerry | Grady Trauma Project* | 200 | 1000 | 1200 | AA—mixed | |
| Ressler, Kerry / Holly Orcutt | NIU Shooting Sample | 70 | 230 | 300 | 80% EA | |
| Aiello, Allison | Detroit Neighborhood Health Study | 72 | 197 | 269 | AA | |
| Liberzon, Israel | Gracy Detroit Mother's Study | 200 | 220 | 420 | 75% EA, 23%AA | |
| Liberzon, Israel | Ohio national Guard Study | 10 | 860 | 870 | 85% EA, 13%AA | |
| Koenen, Karestan | Nurses Health Study II | 170 | 1463 | 1633 | EA | |
| Kessler, Ronald | World Mental Health Surveys | 318 | 6969 | 7287 | Other | |
| Amstadter, Ananda | Service Experience and Alcohol Preference Study | 80 | 80 | 160 | 80% EA, 20%AA | |
| Amstadter, Ananda | Disaster-affected adolescents and families | 82 | 698 | 780 | 70% EA, 25% AA | |
| Yehuda, Rachel | Improving PTSD outcomes in OIF/OEF returnees | 121 | 300 | 421 | Mixed | |
| Yehuda, Rachel | Suicidality and PTSD | 90 | 0 | 90 | Mixed | |
| Yehuda, Rachel | Holocaust PTSD | 45 | 0 | 45 | EA | |
| Feder, Adriana | World Trade Center responders | 50 | 200 | 250 | Mixed | |
| Baker, Dewleen | Marine Resiliency Study* | 117 | 583 | 700 | EA 60% | |
| Stein, Murray | Army STARRS | 1800 | 12200 | 14000 | ||
| Bradley, Bekh | Genetic and Environmental Risk/Resilience Factors for Posttraumatic Stress Disorder in OEF/OIF Veterans | 200 | 600 | 800 | AFR | |
| Beckham, Jean | MIRECC* | 152 | 758 | 910 | Mixed | |
| Herringa, Ryan | Neural Basis of Emotion Regulation in PTSD | 50 | 50 | 100 | ||
| Bisson, Jonathan | Wales PTSD Study | 462 | 960 | 1422 | EA | |
| Hollegaard, Mads | Danish Blood Spot Cohort | 20000 | 20000 | 40000 | EA | |
| Risbrough, Victoria | Norman VA exposure therapy | 200 | 0 | 200 | 60% EA | |
| Subtotal | 25489 | 51368 | 76857 | |||
| TOTAL | 48596 | 99510 | 148158 | |||
Abbreviations: AA, African American ancestry; EA, European American ancestry; PGC, Psychiatric Genomics Consortium; PTSD, posttraumatic stress disorder. *Study contributing more than one wave of data.