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Genetically increasing adult hippocampal neurogenesis does not affect the HPA axis response to acute stress. (a) Experimental timeline. (b and c) There were no differences between vehicle and TAM groups in plasma CORT levels before or at various time points following 30 min of restraint stress or immediately following 15 min in a novel cage (P>0.05). n=4–11/group. All error bars represent SEM. CORT, corticosterone; HPA, hypothalamic–pituitary–adrenal; TAM, Tamoxifen.
