Author response image 3. Influence of selective presynaptic GABAB receptor antagonist CGP36216 on the effect of morphine on the firing in VTA-DA neurons of mice.
(A) Representative spontaneous firing traces recorded before and after morphine (10 μM) in the presence of CGP36216 (100 μM). (B) Time course of spontaneous firing before and after morphine in the presence of CGP36216 (100 μM) (n = 6). (C) Average frequency of spontaneous firing before and after morphine (10 μM) in the presence of CGP36216 (100 μM) (n = 6, P > 0.05, compared to CGP36216 before morphine).