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Activation of RXFP1 receptors with relaxin and ML290.
| Ligand | RLN | ML290 |
|---|---|---|
| Receptor | ||
| Human | *** | *** |
| Macaque | *** | *** |
| Pig | *** | *** |
| Guinea pig | *** | No |
| Guinea pig/human | *** | * |
| Rabbit 1 and 2 | No | ** |
| Human/rabbit | ** | ** |
| Rabbit 1(2)/human | No | ** |
| Mouse | *** | No |
*Weak, **intermediate, ***strong activation of the receptor.
