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. 2015 Aug 3;2015:213750. doi: 10.1155/2015/213750

Table 2.

Top ten genes predicted for ProSim, PRINCE, RWR, and DADA.

Breast cancer Colorectal cancer
ProSim PRINCE RWR DADA ProSim PRINCE RWR DADA
ATM NBN PIK3R1 PIK3R1 TP53 BRCA1 TP53 TP53
PPP1R13L TIE1 HTT FNTA JUN MSH2 AKT1 AURKA
FOSL2 BRCA1 CD44 ATM PIK3R1 MLH1 AKT RHOA
ERBB4 MSH2 CALM1 HTT HTT EP300 IL3 RET
BRIP1 PATZ1 JUN SHOC2 NRAS AKT1 NRAS NTRK1
HIP1 DGCR2 MAPK3 RASSF2 PSEN1 BUB1B BRCA2 CCND1
UBE2K ATM TPX2 CD44 CTNNB1 OGG1 BUB1B BUB1B
RALGDS MRE11A SVIL CALM1 CBL RNF139 LYN BRCA2
FOXG1 H2AFX RAF1 JUN AKT1 APC AURKA EP300
PLK1 TERF2 PSEN1 RAF1 VAV1 EXO1 HNF1A GABRB1

Lung cancer Diabetes mellitus
ProSim PRINCE RWR DADA ProSim PRINCE RWR DADA

PPP1R13L TP53 PPP1R13L IMPDH2 TP53 RHOA AKT1 AKT1
ERBB4 VRK1 MAP3K8 APLP2 JUN MAFA PLN INS
PLK1 TP53RK IGF1R PLK1 PIK3R1 BSCL2 PSEN1 PSEN1
BRD7 ERBB4 BRD7 ICMT HTT SLC2A2 LYN JUN
UBE2K CDKN2A UBE2K GSTM4 HNF1A HNF4A HNF1A HNF1A
EGFR TP53INP1 HUWE1 RAD17 PSEN1 INS PCBD1 TP53
TAPBP TAG TAPBP KLF4 LYN IAPP CASP8 ALB
UHMK1 EGFR UHMK1 CASP8 CBL NEUROD1 PIK3R1 NEUROD1
MAP3K8 RRM2 DGCR2 PIAS1 AKT1 GATA5 HTT CEBPA
HIP1 CUL9 HIP1 FOSL2 VAV1 MAP3K13 EP300 RAC3

Prostate cancer Alzheimer's disease
ProSim PRINCE RWR DADA ProSim PRINCE RWR DADA

TP53 NBN TP53 TP53 TP53 HSD17B10 AKT1 AKT1
JUN BRIP1 RNASEL RNASEL JUN BACE2 PAX2 SFRP2
HTT JUN PAX2 AR HTT TP53 CASP8 PAX2
CD44 BRCA1 ERBB2 ABCE1 APBB2 JUN PSEN1 CASP8
BARD1 HTT CD19 AKT1 PSEN1 HADHB APBB3 WT1
CD82 RAD50 BACE2 ERBB2 LYN NAE1 BLMH PSEN1
ERBB2 TP53 CASP8 CASP8 VAV1 APLP2 MAPK8 RAC3
REL MRE11A TSG101 BUB1B CCND1 BLMH WT1 RB1
SLPI ATM ATM CCNE1 CASP8 APBB1 SFRP2 MAPK8
JUNB BRCA2 CCND1 STAT5A KIT F12 RAC3 RHOA