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Selection of library against ADAMTS-4. (a) The triazine library. (b) The cube corresponding to 4-(aminomethyl)benzoic acid as cycle 2 is shown in detail. The copy number of the selected species is indicated by the continuous color and size of the points (darker and bigger points indicate higher copy number). The structure shown at the bottom represents the family of compounds defined by a line along the BB1 axis (arrow).
