TABLE 6.

Comparison of mutations in wild-type and mutL E. faecium and E. coli

Type of mutation (expected)	E. faeciuma		E. coli
	MutL (Apr and Vmr)	Wild type (Rifr)	MutL (neutral)	Wild type (neutral)
Mutation rate	2.9 × 10−8	1.4 × 10−8	3.0 × 10−8	2.2 × 10−10
% nonsynonymous (70)	85	88	40	41
% missense (85)	96	84	47	43
% transitions	78	32	98	57
% insertions and deletions	35	5	15	7

^aAp^r, ampicillin resistance; Vm^r, vancomycin resistance; Rif^r, rifampin resistance.