FIG 5.

Salinomycin and monensin block oocyst development in the mosquito. P. falciparum stage V gametocytes of a transgenic hsp70-GFP::luc reporter strain were incubated for 24 h with different doses of compounds and fed to A. stephensi mosquitoes. (a and b) Luminescence intensities in individual mosquitoes as a function of the compound concentration indicated on the x axis. (c and d) Oocyst prevalence (percentage of infected mosquitoes) as a function of the compound concentration indicated on the x axis.