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. 2015 Aug 14;59(9):5631–5640. doi: 10.1128/AAC.00850-15

TABLE 3.

In vitro activities of CANBEF-24 alone and in combination with caspofungin, voriconazole, amphotericin B, or staurosporine against A. fumigatus Af293

Drug Drug MIC (μg/ml)
CANBEF-24 MIC (μM)
FICI
Alone Comb.a Alone Comb.
Caspofungin 128 8.00 3.13 0.78 0.31
Voriconazole 1.00 2.00 3.13 1.56 2.50
Amphotericin B 0.50 0.06 6.25 3.13 0.63
Staurosporine 5.00 2.50 6.25 3.13 1.00
a

Comb., in combination.