TABLE 4.
Prevalence of Pfdhfr and Pfdhps single and haplotype mutations among febrile pregnant women presenting at outpatient clinicsa
| Pfdhfr and Pfdhps haplotype(s) | Prevalence of Pfdhfr and Pfdhps mutationsb |
|---|---|
| dhfr 51I | 111/111 (100) |
| dhfr 59R | 112/116 (97) |
| dhfr 108N | 120/120 (100) |
| dhps 437G | 120/120 (100) |
| dhps 540E | 119/120 (99) |
| dhps 581G | 8/103 (8) |
| dhps 613S | 0/111 (0) |
| dhfr double mutant 51I+108N | 111/111 (100) |
| dhfr double mutant 59R+108N | 112/116 (97) |
| dhps double mutant 437G+540E | 119/120 (99) |
| dhfr triple mutant 51I+59R+108N | 107/110 (97) |
| Quadruple mutant (51I+59R+108N)+437G | 107/110 (97) |
| Quintuple mutant (51I+59R+108N)+(437G+540E) | 106/110 (96) |
| Sextuple mutant (51I+59R+108N)+(437G+540E+581G) | 8/101 (8) |
a
The proportion of P. falciparum-positive mutations was 128/998 (12.8%).
b
Prevalence data are expressed as follows: number of mutations/total number of samples tested (%).