TABLE 3.
QnrB1 mutant | No. of expts | Fold change |
P valuec | |
---|---|---|---|---|
Median (ratiob) | Interquartile range | |||
Interaction with GyrA | ||||
Wild type | 14 | 404 (1) | 317–602 | |
ΔloopA | 5 | 372 (0.92) | 161–844 | 0.893 |
ΔloopB | 8 | 175 (0.43) | 128–294 | 0.012 |
ΔloopA+B | 8 | 104 (0.26) | 56–230 | 0.012 |
Interaction with GyrB | ||||
Wild type | 14 | 3,587 (1) | 1,582–10,826 | |
ΔloopA | 6 | 2,621 (0.73) | 1,523–6,572 | 0.028 |
ΔloopB | 5 | 16,517 (4.60) | 6,435–18,909 | 0.080 |
ΔloopA+B | 5 | 14,242 (3.97) | 6,797–25,222 | 0.080 |
Interaction with GyrBA | ||||
Wild type | 9 | 3,777 (1) | 2,368–5,436 | |
ΔloopA | 5 | 219 (0.06) | 63–455 | 0.043 |
ΔloopB | 9 | 3,285 (0.87) | 2,419–6,625 | 0.441 |
ΔloopA+B | 9 | 4,926 (1.30) | 3,962–6,450 | 0.110 |