Distribution of MICs (mg/liter) of ceftazidime (CAZ), cefepime (CPM), and piperacillin-tazobactam (PIP-TAZ). The MIC breakpoints for resistance were as follows: ceftazidime, ≥16 mg/liter; cefepime, ≥16 mg/liter; and piperacillin-tazobactam, ≥128/4 mg/liter. For cefepime, isolates with MICs between 4 and 8 mg/liter (susceptible-dose dependent) were susceptible.