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Implication of caspases in cell death induced by compound 5 in Jurkat cells. Cells were treated with compound 5 for 6 or 24 h in the presence or in the absence of the general caspase inhibitor z-VAD-fmk. Membrane integrity was analyzed by flow cytometry after the cells were stained with 7-AAD, as indicated in the Experimental Section. Results are mean ± SD of two independent experiments.
